• Genome-Wide DNA Methylation in Treatment-Naïve Ulcerative Colitis 

      Taman, Hagar; Fenton, Christopher Graham; Hensel, Inga Viktoria; Anderssen, Endre; Florholmen, Jon; Paulssen, Ruth H (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-22)
      <p><i>Background and Aims</i>: The aim of this study was to investigate the genome-wide DNA methylation status in treatment-naïve ulcerative colitis [UC], and to explore the relationship between DNA methylation patterns and gene expression levels in tissue biopsies from a well-stratified treatment-naïve UC patient group.</p> <p><i>Methods</i>; Mucosal biopsies from treatment-naïve patients [n = ...
    • Transcriptomic Landscape of Treatment-Naïve Ulcerative Colitis 

      Taman, Hagar; Fenton, Christopher Graham; Hensel, Inga Viktoria; Anderssen, Endre; Florholmen, Jon; Paulssen, Ruth H (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-10)
      Background and Aims: Ulcerative colitis [UC] is a chronic inflammatory disease that effects the gastrointestinal tract and is considered one of the most prominent and common forms of inflammatory bowel disease [IBD]. This study aimed to define and describe the entire transcriptomic landscape in a well-stratified, treatment-naïve UC patient population compared ...